Tài liệu miễn phí Hoá học
Download Tài liệu học tập miễn phí Hoá học
Preparation of ethyl levulinate from wheat stalk over Zr(SO4)2/SiO2
The results showed that the active component Zr(SO4 )2 was successfully adhered to the mesoporous SiO2 , and the acid amount of Zr(SO4)2/SiO2 increased with the increasing of the Zr(SO4)2 loadings. Finally, the wheat stalk was used as raw material and depolymerized over Zr(SO4)2/SiO2 to produce ethyl levulinate (EL). The reaction mixture was separated and purified by filtration and vacuum distillation. The kinetic characteristics and the reaction pathway were also studied. A comparative study showed that 20 wt.% Zr(SO4)2/SiO2 exhibited higher catalytic activity. When reaction temperature, time, catalyst dosage and Zr(SO4)2 loadings were 190 °C, 50 min, 20 wt.% and 30 wt.%, the EL yield reached a maximum of 17.14%. The relative content of EL exceeded 90% after three steps of distillation.
4/3/2023 11:45:16 PM +00:00
Theoretical investigation on the addition reaction of the germylenoid H2GeLiCl with acetone
In this work, theoretical calculations were performed on the addition reaction of the germylenoid H2 GeLiCl with acetone. The DFT M06-2X method was used to optimize the geometries of the whole stationary points on the potential energy surfaces and the QCISD method to calculate the single-point energy. The results reveal that the addition reaction of H2 GeLiCl with acetone firstly generates an oxagermacyclopropane c-H2GeOC(CH3)2 and then c-H2GeOC(CH3)2 further reacts with acetone along two possible pathways, pathway I and pathway II, in which the 2,4-dioxagermolane is formed at the end of pathway I and 2,5-dioxagermolane is formed at the end of pathway II, respectively.
4/3/2023 11:45:05 PM +00:00
Synthesis and characterization of benzodioxinone mono-telechelics and their use in block copolymerization
Poly(methyl methacrylate) (PMMA) and poly(ethylene glycol) methyl ether (mPEG)-based monotelechelics were quantitatively prepared by copper (I)-catalyzed azide/alkyne cycloaddition (CuAAC) click reactions using azido-terminated polymers and alkyne functional benzodioxinones. The monotelechelic containing dimethyl moities (2,2-dimethyl-5-(prop-2-yn-1-yloxy)-4Hbenzo[d][1,3]dioxin-4-one) was heat-sensitive, whereas the monotelechelic containing diphenyl moieties (2,2-diphenyl-5-(prop-2-yn1-yloxy)-4H-benzo[d][1,3]dioxin-4-one) was UV light sensitive.
4/3/2023 11:44:55 PM +00:00
Turkish perlite supported nickel oxide as the heterogeneous acid catalyst for a series of Claisen–Schmidt condensation reactions
Potentially active and eco-friendly solid acid catalysts have been synthesized by loading different weight percentages (10, 15, and 50) of nickel oxide on thermally activated Turkish perlite through the deposition-precipitation method. Structural features of prepared catalysts were analyzed using BET surface area analysis, X-ray diffraction, scanning electron microscope (SEM), SEM-EDX, transmission electron microscopy (TEM), Fourier-transform infrared (FT-IR), pyridine adsorbed FT-IR, UV-Vis diffuse reflectance spectroscopy (DRS), and thermogravimetric analysis (TGA) techniques. Pyridine adsorbed FT-IR analysis confirmed the presence of the optimum amount of Bronsted acidic sites in a catalyst having 15 wt.
4/3/2023 11:44:46 PM +00:00
Green biosynthesis, characterization, and cytotoxic effect of magnetic iron nanoparticles using Brassica Oleracea var capitata sub var rubra (red cabbage) aqueous peel extract
The green method of nanoparticle synthesis, which is an environment and living-friendly method, is an updated subject that has appeared as an alternative to conventional methods such as physical and chemical synthesis. In this presented study, the green synthesis of magnetic iron oxide nanoparticles (IONPs) from iron (III) chloride by using Brassica oleracea var. capitata sub.var. rubra aqueous peel extract has been reported. The prepared IONPs were characterized with fourier-transform infrared spectroscopy (FTIR), ultraviolet-visible spectroscopy (UV-VIS), zeta potential, scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX).
4/3/2023 11:44:38 PM +00:00
Feature of catalysis on bimetallic alloys Zr with V, Mo, and Fe in the reaction of methanol oxidation
Catalytic behaviors of bimetallic catalysts-alloys of zirconium with vanadium, molybdenum, and iron was investigated in the oxidative dehydrogenation of methanol. The conditions for the formation of the catalyst’s active surface were revealed. The conversion of methanol into formaldehyde, dimethyl ether, and dimethoxymethane on bimetallic catalysts was studied. The characterization of catalysts was performed by XRD, XPS, and SEM. It was shown that the activity of samples increases after О2 + Н2 treatment and was associated with segregation of the active components of alloys (V, Mo) on the surface of catalysts and realization of their optimal oxidation state under catalysis conditions.
4/3/2023 11:44:26 PM +00:00
Impact of graphitic carbon nitrides synthesized from different precursors on Schottky junction characteristics
Graphitic carbon nitride (g-CN) has gained wide interest in many areas, such as energy and the environmental remediation as a layered polymeric semiconductor that allows the formation of catalytically active Schottky junctions due to its proper electronic band structure. Interestingly, although it is known that the precursors used in the synthesis, can influence the properties of the g-CN, no detailed study on these effects on Schottky junctions could be found in the literature. In this research, the effects of g-CNs synthesized by thermal polycondensation of different precursors on the photocatalytic efficiency of Schottky junctions were investigated.
4/3/2023 11:44:15 PM +00:00
Evaluation of quercetin as a potential β-lactamase CTX-M-15 inhibitor via the molecular docking, dynamics simulations, and MMGBSA
Antimicrobial resistance (AMR) threatens millions of people around the world and has been declared a global risk by the World Economic Forum. One of the important AMR mechanisms in Enterobacteriaceae is the production of extended-spectrum β-lactamases. The most common ESBL, CTX-M β-lactamases, is spread to the world by CTX-M-15 and CTX-M-14. Sulbactam, clavulanic acid, and tazobactam are first-generation β-lactamase inhibitors and avibactam is a new non-β-lactam β-lactamase inhibitor. We studied that avibactam, sulbactam, clavulanic acid, tazobactam, and quercetin natural flavonoids were docked to target protein CTXM-15. Subsequently, the complexes were simulated using the molecular dynamics simulations method during 100 ns for determining the final binding positions of ligands.
4/3/2023 11:44:00 PM +00:00
Multiple objective optimization of air assisted liquid-liquid microextraction combined with solidified floating organic drop microextraction for simultaneous determination of trace copper and nickel
The impact of rising levels of various heavy metals in the environment from multiple industrial, agriculture, domestic, and technological activities is of great concerns, as heavy metals cause serious health effects for both humans and wildlife. An effective and green chemistry procedure was used for simultaneous extraction of ultra-trace copper and nickel ions in natural waters (e.g. river and well waters) by air assisted liquid-liquid microextraction combined with solidified floating organic drop microextraction (AALLMESFOD). The extraction of metal ions was conducted in a timescale of several minutes by conversion to metal chelates using sodium diethyldithiocarbamate (DDTC) as a chelating agent prior to AALLME-SFOD procedure, and 1-dodecanol as an extraction solvent to initiate the phase separation of the complex.
4/3/2023 11:43:52 PM +00:00
Binding of permanganate anion to pentaammineazidocobalt(III) cation in solution and solid phases: Synthesis, characterization, X-ray structure, and genotoxic effects of [Co(NH3)5N3](MnO4)2 ⋅H2O
A pentaammineazidocobalt(III) complex, [Co(NH3)5N3](MnO4)2XH2O has been synthesized by an one-pot synthesis method. It was characterized by studies such as infrared (IR) and UV-visible spectroscopy. The single crystal X-ray structure analysis revealed that the title complex crystallizes in space group Cc. The cobalt center is six coordinated with slightly octahedral geometry. The supramolecular architecture is also formed by intermolecular N-H…O (anion and H2O) and Mn-O…O-H hydrogen bonds. The binding property of the cation, [Co(NH3)5N3]2+ with the anion, MnO4 – has also been determined (in solution phase) with the help of UV-visible spectroscopic titrations.
4/3/2023 11:43:42 PM +00:00
Novel mixed ligand coordination compounds of some rare earth metal cations containing acesulfamato/N,N-diethylnicotinamide
The mixed ligand coordination compounds containing acesulfamato and N,N-diethylnicotinamide biomolecules of some rare earth metal cations (Eu3+, Tb3+, Ho3+, Er3+ and Yb3+) were synthesized, and their structural properties were investigated. Possible structural formulas have been proposed by determining the chemical composition of molecules (elemental analysis), binding properties (infrared spectroscopy, mass analysis, solid-state UV-vis spectroscopy), thermal degradation properties (TGA / DTA curves). Based on the data collected, it is suggested that rare earth metal cations with a 3+ oxidation state have sextet coordination. The geometries of the structures were thought to be distorted octahedral.
4/3/2023 11:43:34 PM +00:00
Detection of bacteria using antimicrobial polymer derived via ring-opening metathesis (romp) pathway
There is growing interest in the detection of bacteria in consumables, for example, in the food and water sectors. In this study, the aim was to produce a polymer-based bacteria biosensor via ROMP (ring opening metathesis polymerization). In the first part of the study, block and random copolymers were synthesized, and their biocidal activities were tested on the glass surface. Interdigitated electrode arrays coated with the polymers possessing the highest activity were used to screen the affinity towards different bacterial strains by monitoring impedance variations in real-time. The polymer-coated electrode could detect gram-positive and gram-negative bacteria strains at a concentration of 107 cfu/mL. The results show that ROMP-based polymer offers bacterial detection and can be used in developing biosensor devices for efficiently detecting pathogenic bacteria.
4/3/2023 11:43:21 PM +00:00
Synthesis of Ni/Al2O3 catalysts via alkaline polyol method and hydrazine reduction method for the partial oxidation of methane
Nickel catalysts supported on γ-Al2 O3 were synthesized in the presence of polyvinylpyrrolidone (PVP) using both alkaline polyol method and hydrazine reduction method while fixing the weight ratio of [(PVP)]/[Ni(CH3COO)2·4H2O] at 2. The effects of hydrazine [N2H5OH]/[Ni] and [NaOH]/[Ni] molar ratios on the structural properties of the catalysts were characterized by transmission electron microscopy (HRTEM) and by X-ray diffraction (XRD). The average of monodispersed Ni nanoparticles ranged between 8.0 and 13.0 nm. The catalytic tests were performed for the partial oxidation of methane in the temperature range of 600–800 °C under a flow rate of 157,500 L kg–1 hr–1 with CH4 /O2 = 2.
4/3/2023 11:43:09 PM +00:00
Phenolic compounds, essential oil composition, and antioxidant activity of Angelica purpurascens (Avé-Lall.) Gill
In this study, methanol extracts (MEs) and essential oil (EO) of Angelica purpurascens (Avé-Lall.) Gill obtained from different parts (root, stem, leaf, and seed) were evaluated in terms of antioxidant activity, total phenolics, compositions of phenolic compound, and essential oil with the methods of 2,2-azino-bis(3ethylbenzo-thiazoline-6-sulfonic acid (ABTS•+), 2,2-diphenyl-1-picrylhydrazil (DPPH•) radical scavenging activities, and ferric reducing/antioxidant power (FRAP), the Folin–Ciocalteu, liquid chromatography− tandem mass spectrometry (LC−MS/MS), and gas chromatography-mass spectrometry (GC−MS), respectively.
4/3/2023 11:43:01 PM +00:00
Synthesis, spectroscopic, thermal, crystal structure properties, and characterization of new Hofmann-Td-type complexes with 3-aminopyridine
In this study, synthesis of two new tetracyanocadmate(II) and tetracyanozincate(II) complexes based on 3-aminopyridine (3AP) and investigation of their structural properties were reported. These complexes were characterized by using vibration spectroscopy, elemental, thermal analysis and single crystal X-ray diffraction (SC-XRD) techniques. Investigation of the elemental, spectral and single crystal data of these complexes showed that the formulas [Cd(3AP)2Zn(μ4 -CN)4]n(1) and [Cd(3AP)2Cd(μ4-CN)4]n(2) fully explained their crystal structure.
4/3/2023 11:42:49 PM +00:00
Scalable activated carbon/graphene based supercapacitors with improved capacitance retention at high current densities
Scalable, highly stable supercapacitor electrodes were developed from the mixture of a tea factory waste based activated carbon (AC) and a low-cost electrochemical exfoliated graphene (EEG). The hybrid electrodes showed notably enhanced stability at high current densities. The AC sample was prepared by chemical method and exposed to a further heat treatment to enhance electrochemical performance. Graphene used in the preparation of hybrid electrodes was obtained by direct electrochemical exfoliation of graphite in an aqueous solution. Detailed structural characterization of AC, EEG, and hybrid material was performed. The original electrochemical performances of AC and EEG were examined in button size cells using an aqueous electrolyte.
4/3/2023 11:42:38 PM +00:00
PAN-based activated carbon nanofiber/metal oxide composites for CO2 and CH4 adsorption: Influence of metal oxide
In the present study, we successfully prepared two different electrospun polyacrylonitrile (PAN) based-activated carbon nanofiber (ACNF) composites by incorporation of well-distributed Fe2O3 and Co3O4 nanoparticles (NPs). The influence of metal oxide on the structural, morphological, and textural properties of final composites was thoroughly investigated. The results showed that the morphological and textural properties could be easily tuned by changing the metal oxide NPs. Even though, the ACNF composites were not chemically activated by any activation agent, they presented relatively high surface areas (SBET) calculated by Brunauer–Emmett– Teller (BET) equation as 212.21 and 185.12 m2/g for ACNF/Fe2O3 and ACNF/Co3O4 composites, respectively.
4/3/2023 11:42:29 PM +00:00
Aspect ratio dependent air stability of PbSe nanorods and photovoltaic applications
Development of unique strategies to overcome Shockley–Queisser (SQ) limit in solar cells has gained a great deal of interest. Multiple exciton generation (MEG) process has been considered as one of the best approaches to the SQ limitation. In this respect, PbSe quantum dots (QDs) and nanorods (NRs) have been regarded as promising solar energy harvesting materials owing to their noticeable MEG yields. Although air stability has been regarded as one of the main disadvantage of PbSe QDs, no study has pointed out to the air sensitivity of PbSe NRs yet.
4/3/2023 11:42:19 PM +00:00
UV-Visible spectroscopic study on multi-staged film formation mechanisms of graphene oxide-doped polystyrene latex (PS latex/GO) nanocomposites
We report the effect of graphene oxide (GO) on film formation and morphological properties of GO-doped polystyrene (PS) latex nanocomposite (PS latex/GO) films using UV-visible absorption spectroscopy and scanning electron microscopy (SEM). PS latex particles were synthesized through emulsion polymerization technique and then nanocomposite blends, each containing different concentrations of GO ranging from 0 wt% to 70 wt%, were obtained. Prepared blends were deposited on glass plates via drop-casting method and coated substrates were annealed at different temperatures between 100 °C and 250 °C. At each annealing temperature, transmitted light intensity of nanocomposite films was recorded. Void closure and Prager-Tirrell models were employed to interpret the film formation behavior. Activation energy of viscous flow (ΔH) decreased from 21.80 kcal·mol-1 to 5.91 kcal·mol-1 when the amount of GO content increased in film composition.
4/3/2023 11:42:09 PM +00:00
Spectrophotometric and colorimetric determination of gallium (III) with p-aminohippuric acid-functionalized citrate capped gold nanoparticles
A new technique for sensing Ga(III) concentration based on polyvinyl alcohol-citrate capped gold nanoparticle–p-aminohippuric acid hybrid (or three-layer core-shell configurations) has been demonstrated. The p-aminohippuric acid capped citrate-gold nanoparticles were comfortably agglomerated in the presence of Ga(III), and the color of the reaction quickly turned from red to violet or blue. Under the detection conditions, a good linear relationship was ideally obtained between the ratio of the absorbance intensity at 620 nm to that at 520 nm (A620/A520). The linear response range, the detection, and quantification limit was 34.9–418.3 μg/L and 7.6 μg/L, and 25 μg/L, respectively
4/3/2023 11:41:59 PM +00:00
High capacity gas capture and selectivity properties of triazatruxene-based ultramicroporous hyper-crosslinked covalent polymer
Tuning the selective sorption features of microporous organic networks is of great importance for subsequent applications in gas uptake and hiding, while it is more attractive in terms of being both time and cost effective to realize these optimizations without using functional groups in the core and linker. “Knitting” is one of the easiest and most used method to obtain a broad scope of hyper-crosslinked polymers on a large scale from aromatic structures that do not contain functional groups for polymerization. By the use of Knitting method, a hypercrosslinked covalent ultramicroporous organic polymer was obtained via stepwise process from using triazatruxene (TAT) as core -a planar indole trimer- through anhydrous FeCl3 catalyzed Friedel–Crafts alkylation using dimethoxybenzene as a linker.
4/3/2023 11:41:49 PM +00:00
3-Hydroxy-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one and 3-hydroxy-6H-benzo[c] chromen-6-one act as on-off selective fluorescent sensors for Iron (III) under in vitro and ex vivo conditions
Regarding the abundant use of metals for different purposes, it becomes more critical from various scientific and technological perspectives to discover novel agents as selective probes for the detection of specific metals. In our previous studies, we have shown that aqueous solutions of natural urolithins (i.e., hydroxyl-substituted benzo[c]chromen-6-one derivatives) are selective Iron (III) sensors in fluorescence assays. In this study, we have extrapolated these findings to another coumarine compound (i.e., 3-Hydroxy-7,8,9,10- tetrahydro-6H-benzo[c]chromen-6-one) and compared the selective metal binding properties with Urolithin B (i.e., 3-Hydroxy-6Hbenzo[c]chromen-6-one).
4/3/2023 11:41:41 PM +00:00
Evaluation of the surface properties of 4-(Decyloxy) benzoic acid liquid crystal and its use in structural isomer separation
The selectivity of 4-(Decyloxy) benzoic acid (DBA) liquid crystal in surface adsorption region (303.2–328.2K) and thermodynamic region (423.2 – 433.2K) was investigated by inverse gas chromatography at infinite dilution (IGC-ID). The selectivity parameters of the structural isomer series named butyl acetate, butyl alcohol, and amyl alcohol series were calculated for the DBA using IGC-ID technique. Additionally, the surface properties including dispersive surface energy (gSD), free energy (DGAS), enthalpy (DHAS), and acidity-basicity constants were calculated with net retention volumes obtained from IGC-ID experiment results. When the DHAS and DGAS are constants, DBA surface was found to be an acidic character (KD/KA@0.89).
4/3/2023 11:41:30 PM +00:00
Synthesis and antioxidant activities of new nickel(II) complexes derived from 4-benzyloxysalicylidene-S-methyl/propyl thiosemicarbazones
Six nickel(II) complexes of the N2 O2 chelating thiosemicarbazones were synthesized using N1-4-benzyloxysalicylidene-Smethyl/propyl thiosemicarbazone and methoxy-substitute-salicylaldehydes in the presence of Ni(II) ion by template reaction. The structures of thiosemicarbazones and nickel(II) complexes were characterized by elemental analysis, UV-Vis, IR, and 1H-NMR spectroscopies. The structure of the N1-4-benzyloxysalicylidene-S-propyl thiosemicarbazone (2) was determined by X-ray single-crystal diffraction method. The total antioxidant capacities of synthesized compounds were evaluated by using cupric reducing antioxidant capacity (CUPRAC) method.
4/3/2023 11:41:21 PM +00:00
Development of a functional impedimetric immunosensor for accurate detection of thyroid-stimulating hormone
In this study, a nonlabeled immunosensor based on covalent immobilization of anti-TSH antibody by using the formation of self-assembled monolayers (SAM) of 4-mercaptophenylacetic acid (4-MPA) and functionalization of carboxyl ends with 1-ethyl-3-(3-dimetilaminopropil) carbodiimide (EDC)/N-Hydroxysuccinimide (NHS) was fabricated for detection of TSH. Immobilization steps including the concentration of 4-MPA, the concentration of anti-TSH antibody, and duration of anti-TSH antibody incubation were optimized by utilizing electrochemical impedance spectroscopy. Under optimal conditions, a sensitive, rapid, and accurate determination of TSH at a concentration range between 0.7 and 3.5 mIU/L was accomplished with a notable linearity and LOD value of 0.034 mIU/L, as well as reproducibility and repeatability.
4/3/2023 11:41:13 PM +00:00
Novel Mannich bases with strong carbonic anhydrases and acetylcholinesterase inhibition effects: 3-(aminomethyl)-6-{3-[4-(trifluoromethyl)phenyl]acryloyl}-2(3H)- benzoxazolones
In this study, a new series of Mannich bases, 3-(aminomethyl)-6-{3-[4-(trifluoromethyl)phenyl]acryloyl}-2(3H)- benzoxazolones (1a–g), were synthesized by the Mannich reaction. Inhibitory effects of the newly synthesized compounds towards carbonic anhydrases (CAs) and acetylcholinesterase (AChE) enzymes were evaluated to find out new potential drug candidate compounds. According to the inhibitory activity results, Ki values of the compounds 1 and 1a–g were in the range of 12.3 ± 1.2 to 154.0 ± 9.3 nM against hCA I, and they were in the range of 8.6 ± 1.9 to 41.0 ± 5.5 nM against hCA II. Ki values of acetazolamide (AZA) that was used as a reference compound were 84.4 ± 8.4 nM towards hCA I and 59.2 ± 4.8 nM towards hCA II.
4/3/2023 11:41:04 PM +00:00
Synthesis of hydroxy benzoin/benzil analogs and investigation of their antioxidant, antimicrobial, enzyme inhibition, and cytotoxic activities
In this study, hydroxy benzoin (1-7), benzil (8-14), and benzoin/benzil-O-β-D-glucosides (15-25) were synthesized to investigate their biological activities. An efficient method for synthesizing hydroxy benzoin compounds (1-7) was prepared from four different benzaldehydes using an ultrasonic bath. Then, antioxidant (FRAP, CUPRAC, and DPPH), antimicrobial (3 Gram (-), 4/6 Gram (+), one tuberculosis and one fungus), and enzyme inhibition (acetylcholinesterase, butyrylcholine esterase, tyrosinase, α-amylase, and α- glucosidase) for the all synthesized compounds (1-25) were evaluated.
4/3/2023 11:40:57 PM +00:00
Electrochemical evaluation of the desloratadine at bismuth film electrode in the presence of cationic surfactant: Highly sensitive determination in pharmaceuticals and human urine by Linear sweep-cathodic stripping voltammetry
In this study, the electrochemical properties of desloratadine, which is in the second generation antihistamines group, were determined by bismuth film electrode (BiFE) in aqueous and aqueous/surfactant solutions. This compound gave an irreversible and diffusion-controlled reduction peak at about –1.65 V by cyclic voltammetry. It was found that the addition of cationic surfactants (cetyltrimethylammonium bromide (CTAB) increased the reduction current signal of desloratadine, while anionic (sodium dodecylsulfate (SDS) and nonionic (Tween 80) surfactants were found to have an adverse effect.
4/3/2023 11:40:41 PM +00:00
The synthesis and characterization of polyorganosiloxane nanoparticles from 3-mercaptopropyltrimethoxysilane for preparation of nanocomposite films via photoinitiated thiol-ene polymerization
This article describes the synthesis of modified silica nanoparticles (SiO2 -MPTMS) via the condensation reaction carried out between silanol moieties of silica nanoparticles and the trialkoxy silyl groups of (3-mercaptopropyl) trimethoxysilane (MPTMS). Then, SiO2-MPTMS nanoparticles in certain amounts (0.5 wt %, 1 wt %, 2.5 wt % and 5 wt %) were incorporated into thiol-ene resins consisting of bisphenol A glycerolate dimethacrylate and trimethylolpropane tris(3-mercaptopropionate) to prepare nanocomposite films via the photoinitiated thiol-ene polymerization in presence of 2,2-Dimethoxy-2-phenylacetophenone 99% as a photoinitiator.
4/3/2023 11:40:28 PM +00:00
Synthesis, spectral characterization, and biological studies of 3,5-disubstituted1,3,4-oxadiazole-2(3H)-thione derivatives
The reaction of 3,4-dichlorophenyl-1,3,4-oxadiazole-2(3H)-thione with piperidine derivatives via Mannich reaction was used to generate eleven novel compounds in moderate to good yields. Synthesized molecules were characterized according to their structure with 1 H NMR, 13C NMR and FT-IR spectral foundations, which were compatible with literature informations. Antimicrobial activity and cytotoxicity studies were done by disc diffusion and NCI-60 sulphordamine B assay methods. The antimicrobial test results revealed that synthesized compounds have better activity against gram-positive species than gram-negative ones.
4/3/2023 11:40:20 PM +00:00