The nuclear receptor ERβ engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading
The nuclear receptor ERβ engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading
The RNA-binding protein Argonaute 2 (AGO2) is a key effector of RNA-silencing pathways It exerts a pivotal role in microRNA maturation and activity and can modulate chromatin remodeling, transcriptional gene regulation and RNA splicing.