TET-dependent regulation of retrotransposable elements in mouse embryonic stem cells
TET-dependent regulation of retrotransposable elements in mouse embryonic stem cells
Ten-eleven translocation (TET) enzymes oxidise DNA methylation as part of an active demethylation pathway. Despite extensive research into the role of TETs in genome regulation, little is known about their effect on transposable elements (TEs), which make up nearly half of the mouse and human genomes.