Systematic analysis of chromatin interactions at disease associated loci links novel candidate genes to inflammatory bowel disease
Systematic analysis of chromatin interactions at disease associated loci links novel candidate genes to inflammatory bowel disease
Genome-wide association studies (GWAS) have revealed many susceptibility loci for complex genetic diseases. For most loci, the causal genes have not been identified. Currently, the identification of candidate genes is predominantly based on genes that localize close to or within identified loci.