Prediction of functional microRNA targets by integrative modeling of microRNA binding and target expression data
Prediction of functional microRNA targets by integrative modeling of microRNA binding and target expression data
We perform a large-scale RNA sequencing study to experimentally identify genes that are downregulated by 25 miRNAs. This RNA-seq dataset is combined with public miRNA target binding data to systematically identify miRNA targeting features that are characteristic of both miRNA binding and target downregulation.