Loss of function of myosin chaperones triggers Hsf1-mediated transcriptional response in skeletal muscle cells
Loss of function of myosin chaperones triggers Hsf1-mediated transcriptional response in skeletal muscle cells
Mutations in myosin chaperones Unc45b and Hsp90aa1.1 as well as in the Unc45b-binding protein Smyd1b impair formation of myofibrils in skeletal muscle and lead to the accumulation of misfolded myosin.