Inference of single-cell phylogenies from lineage tracing data using Cassiopeia
Inference of single-cell phylogenies from lineage tracing data using Cassiopeia
The pairing of CRISPR/Cas9-based gene editing with massively parallel single-cell readouts now enables large-scale lineage tracing. However, the rapid growth in complexity of data from these assays has outpaced our ability to accurately infer phylogenetic relationships.