HistoneHMM: Differential analysis of histone modifications with broad genomic footprints
HistoneHMM: Differential analysis of histone modifications with broad genomic footprints
ChIP-seq has become a routine method for interrogating the genome-wide distribution of various histone modifications. An important experimental goal is to compare the ChIP-seq profiles between an experimental sample and a reference sample, and to identify regions that show differential enrichment.