FBXO32, encoding a member of the SCF complex, is mutated in dilated cardiomyopathy
FBXO32, encoding a member of the SCF complex, is mutated in dilated cardiomyopathy
Dilated cardiomyopathy (DCM) is a common form of cardiomyopathy causing systolic dysfunction and heart failure. Rare variants in more than 30 genes, mostly encoding sarcomeric proteins and proteins of the cytoskeleton, have been implicated in familial DCM to date.