DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer
DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer
The APOBEC3 family of cytidine deaminases mutate the cancer genome in a range of cancer types. Although many studies have documented the downstream effects of APOBEC3 activity through next-generation sequencing, less is known about their upstream regulation.