Differentiated demographic histories and local adaptations between Sherpas and Tibetans
Differentiated demographic histories and local adaptations between Sherpas and Tibetans
The genetic relationships reported by recent studies between Sherpas and Tibetans are controversial. To gain insights into the population history and the genetic basis of high-altitude adaptation of the two groups, we analyzed genome-wide data in 111 Sherpas (Tibet and Nepal) and 177 Tibetans (Tibet and Qinghai), together with available data from present-day human populations.