Autosomal genetic control of human gene expression does not differ across the sexes
Autosomal genetic control of human gene expression does not differ across the sexes
Despite their nearly identical genomes, males and females differ in risk, incidence, prevalence, severity and age-at-onset of many diseases. Sexual dimorphism is also seen in human autosomal gene expression, and has largely been explored by examining the contribution of genotype-by-sex interactions to variation in gene expression.