Kinetics for Bioscientist

Peter Klappa Kinetics for Bioscientist Download free ebooks at bookboon.com 2 Kinetics for Bioscientist © 2009 Peter Klappa & Ventus Publishing ApS ISBN 978-87-7681-469-4 Download free ebooks at bookboon.com 3 Kinetics for Bioscientist Contents Contents Preface 8 1. Why a Bioscientist should care about kinetics 10 1.1. Introduction and learning outcomes 10 1.2. Problem: Elimination of alcohol from the body 10 1.3. Problem: Growth of an E.coli culture 11 1.4. Problem: Cancer 12 1.5. Summary 17 2. Rates, speeds and velocities 18 2.1. Introduction and learning outcomes 18 2.2. Defi nitions 18 2.3. Average and instantaneous rates 20 2.4. Working with instantaneous rates 21 2.5. Summary 30 3. Zero Order Reactions 32 3.1. Introduction and learning outcomes 32 3.2. Some definitions for zero order reactions 32 3.3. Developing the tools for a zero order reaction 33 3.4. Problem: Elimination of a drug from the metabolism 40 The next step for top-performing graduates Masters in Management Designed for high-achieving graduates across all disciplines, London Business School’s Masters in Management provides specific and tangible foundations for a successful career in business. This 12-month, full-time programme is a business qualification with impact. In 2010, our MiM employment rate was 95% within 3 months of graduation*; the majority of graduates choosing to work in consulting or financial services. As well as a renowned qualification from a world-class business school, you also gain access to the School’s network of more than 34,000 global alumni – a community that offers support and opportunities throughout your career. For more information visit www.london.edu/mm, email mim@london.edu or give us a call on +44 (0)20 7000 7573. * Figures taken from London Business School’s Masters in Management 2010 employment report Download free ebooks at bookboon.com 4 Kinetics for Bioscientist Contents 3.5. Problem: Transport of growth hormone receptor to cell membrane 44 3.6. Which equation should I use to calculate the product of a reaction? 46 3.7. Problem solving strategies 47 3.8. Equations for zero order reactions 50 3.9. More practice questions 51 4. First order reaction 53 4.1. Introduction and learning outcomes 53 4.2. Some defi nitions for first order reactions 53 4.3. Developing the tools for a first order reaction 56 4.4. Problem: Elimination of a drug from the metabolism 69 4.5. Problem: Radioactive decay 72 4.6. Problem: Degradation of a receptor/ligand dimer 74 4.7. Problem: Growth of a population 79 4.8. Problem Solving Strategies 83 4.9. Equations for a first order reaction 86 4.10. More practice questions 87 5. Second order reaction – a special case 92 5.1. Introduction and learning outcomes 92 5.2. Some general definitions of a second order reaction 92 5.3. Developing the tools for a second order reaction 94 5.4. Problem: Dimerization of the receptor for a growth hormone 99 5.5. Problem: Formation of active reverse transcriptase dimers 102 5.6. Problem solving strategies 107 Teach with the Best. Learn with the Best. Agilent offers a wide variety of affordable, industry-leading electronic test equipment as well as knowledge-rich, on-line resources —for professors and students. We have 100’s of comprehensive web-based teaching tools, lab experiments, application notes, brochures, DVDs/ CDs, posters, and more. © Agilent Technologies, Inc. 2012 See what Agilent can do for you. www.agilent.com/find/EDUstudents www.agilent.com/find/EDUeducators u.s. 1-800-829-4444 canada: 1-877-894-4414 Download free ebooks at bookboon.com 5 ... - tailieumienphi.vn