Effect of oxytetracycline-dosing on the growth, safety and intestinal histology of nile tilapia, Oreochromis niloticus (L.) juveniles
Effect of oxytetracycline-dosing on the growth, safety and intestinal histology of nile tilapia, Oreochromis niloticus (L.) juveniles
The present study was carried out to evaluate the effect of oxytetracycline (OTC)- dosing at five different concentrations, viz., 0 mg (0X), 80 mg (1X), 240 mg (3X), 400 mg (5X) and 800 mg (10X) kg-1 biomass day-1 for 30 consecutive days on the growth, safety and intestinal histology of Nile tilapia, Oreochromis niloticus (L.) juveniles. The OTC-residues in the edible muscle were detected at scheduled intervals by LCMS/MS. A dose-dependent decline in feed intake, biomass and survival were record