Polymorphisms in autophagy genes are genetic susceptibility factors in glioblastoma development
Polymorphisms in autophagy genes are genetic susceptibility factors in glioblastoma development
Glioblastoma is the most aggressive and common malignant primary brain tumor in adults. Many genetic, epigenetic and genomic mutations have been identified in this tumor, but no driving cause has been identified yet for glioblastoma pathogenesis.