Activated TAZ induces liver cancer in collaboration with EGFR/HER2 signalling pathways
Activated TAZ induces liver cancer in collaboration with EGFR/HER2 signalling pathways
Liver cancer is a major global health concern due to the steady increases in its incidence and mortality. Transcription factors, yes-associated protein (YAP) and WW domain-containing transcription regulator protein 1 (WWTR1, also known as TAZ) have emerged as critical regulators in human hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC), the two major types of primary liver cancer.