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Association of serum 25-hydroxyvitamin D with metabolic syndrome and type 2 diabetes: A one sample Mendelian randomization study
Vitamin D deficiency has been associated with type 2 diabetes (T2D) and metabolic syndrome (MS) and its components. However, it is unclear whether a low concentration of vitamin D is the cause or consequence of these health conditions. Thus, this study aimed to evaluate the association of vitamin D concentrations and its genetic risk scores (GRSs) with MS and its component diseases, such as T2D, in middle-aged and elderly participants from rural eastern China.
4/7/2023 1:17:00 PM +00:00
The rising tide of dementia deaths: triangulation of data from three routine data sources using the Clinical Practice Research Datalink
Dementia is currently the leading certified underlying cause of death in England. We assess how dementia recording on Office for National Statistics death certificates (ONS) corresponded to recording in general practice records (GP) and Hospital Episode Statistics (HES).
4/7/2023 1:16:51 PM +00:00
Fear of falling is as important as multiple previous falls in terms of limiting daily activities: A longitudinal study
Fear of falling and previous falls are both risk factors that affect daily activities of older adults. However, it remains unclear whether they independently limit daily activities accounting for each other.
4/7/2023 1:16:41 PM +00:00
Association between frailty and ischemic heart disease: A systematic review and meta-analysis
Frailty is increasingly reported among older adults with cardiovascular diseases and it has been demonstrated to increase negative health outcomes and mortality. To date, no systematic review of the evidence is available regarding the association between frailty and ischemic heart disease (IHD). We performed a systematic review of literature and a meta-analysis to assess the association between frailty and IHD.
4/7/2023 1:16:35 PM +00:00
Association of life course socioeconomic status and adult height with cognitive functioning of older adults in India and China
Cognitive functioning is an important measure of intrinsic capacity. In this study, we examine the association of life course socioeconomic status (SES) and height with cognitive functioning among older adults (50+) in India and China. The age pattern of cognitive functioning with measures of life course socioeconomic status has also been examined.
4/7/2023 1:16:28 PM +00:00
Oral status of older people in medium to long-stay health and social care setting: A systematic review
Older patients who spend long periods hospitalized or those who are in a situation of institutionalization represent a risk group in this regard, as many of them suffer a degree of dependence and need help to perform the basic tasks of personal care.
4/7/2023 1:16:21 PM +00:00
Disability trajectories prior to death for ten leading causes of death among middleaged and older adults in Taiwan
Prolonged life expectancy is associated with increased prevalence of chronic diseases. The aim of this study was to determine the different disability trajectories for the top ten leading causes of death in Taiwan.
4/7/2023 1:16:15 PM +00:00
Frailty increases the risk for developing urinary tract infection among 79,887 patients with diabetic mellitus and chronic kidney disease
Patients with diabetic mellitus (DM) and chronic kidney disease (CKD) are at an increased risk of urinary tract infection (UTI) due to their altered immunological integrity. These patients are similarly prone to developing frailty, a state of cumulative health deficits involving multiple domains and leading to adverse outcomes.
4/7/2023 1:16:08 PM +00:00
Describing people with cognitive impairment and their complex treatment needs during routine care in the hospital – cross-sectional results of the intersec-CM study
Cognitive impairment is an important determinant in health care. In the acute hospital setting cognition has a strong impact on treatment and care. Cognitive impairment can negatively affect diagnostics and treatment success. However, little is known about the individual situation and specific risks of people with cognitive impairments during hospital stays.
4/7/2023 1:16:02 PM +00:00
Psychometric validation of the Chinese version of the PaArticular Scales among elderly residents in long-term care facilities with joint contractures
Joint contractures, which affect activity, participation, and quality of life, are common complications of neurological conditions among elderly residents in long-term care facilities. This study examined the reliability and validity of the Chinese version of the PaArticular Scales in a population with joint contractures.
4/7/2023 1:15:55 PM +00:00
A novel Longshi Scale measured activity of daily living disability in elderly patients affected by neurological diseases: A multicenter cross-sectional study in China
Ability in the activities of daily life is often impaired in the older adults with a neurological disease. The Barthel Index is an instrument used worldwide to assess such ability. The Longshi Scale is a picture-based alternative, but its effectiveness has not been evaluated with older adult subjects. This study was to determine whether the Longshi Scale can effectively quantify the ability of older adults in the activities of daily living by comparing its ratings with those using the Barthel Index.
4/7/2023 1:15:48 PM +00:00
A mixed-methods study evaluating the impact of an excursion-based social group on quality of life of older adults
Social isolation is an increasing concern for older adults who live in the community. Despite some availability of social support programs to address social isolation, their effectiveness is not routinely measured. This study aimed to evaluate an innovative excursion-based program offering unique social experiences to older adults receiving aged care services.
4/7/2023 1:15:40 PM +00:00
Promoting neuroplasticity and neuropsychological functioning in frailty through an app-based sensorimotor training: Study protocol for a randomized trial
Frailty is characterized by an age-related decline in multiple physiological systems, leading to a high vulnerability to stressors, adverse health outcomes, and low quality of life. Neuroscientific models of pathological aging emphasize the loss of sensorimotor stimulation and reduced neuromodulatory capacities as core processes in age-related cognitive and bodily decline, which may be associated with maladaptive plastic changes in the brain.
4/7/2023 1:15:33 PM +00:00
Multimorbidity patterns in old adults and their associated multi-layered factors: A cross-sectional study
Influenced by various factors such as socio-demographic characteristics, behavioral lifestyles and socio-cultural environment, the multimorbidity patterns in old adults remain complex. This study aims to identify their characteristics and associated multi-layered factors based on health ecological model.
4/7/2023 1:15:26 PM +00:00
Structural equation model of affecting factors on elder abuse to patients under hemodialysis by family caregivers
The objectives of the present study were to determine the prevalence of older adults with hemodialysis (HD) abuse by family caregivers and the factors affecting it. The results of the present study showed that the prevalence of elder abuse by family caregivers among the older adults under hemodialysis is high. Providing psychological counseling can reduce the consequences of elder abuse.
4/7/2023 1:15:20 PM +00:00
Contribution of IQ in young adulthood to the associations of education and occupation with cognitive ability in older age
Studies suggest that a higher education and occupation are each associated with a higher late-life cognitive ability, but their inter-relationships in their association with cognitive ability and the contribution of peak IQ in young adulthood (‘pre-morbid IQ’) often remain unclear.
4/7/2023 1:15:13 PM +00:00
Is achieving 7,000 steps/day crosssectionally and prospectively associated with older adults’ lower-extremity performance?
Evidence regarding the association between daily steps recommendation and older adults’ lower limb strength is lacking; thus, this study investigated whether taking at least 7,000 steps/day is cross-sectionally and prospectively related to lower-extremity performance in older Taiwanese adults.
4/7/2023 1:15:07 PM +00:00
Soluble ST2 and risk of cognitive impairment after acute ischemic stroke: A prospective observational study
Soluble suppression of tumorigenesis-2 (sST2) was reported to be associated with cognitive performance and risk of incident stroke. However, the impact of sST2 on cognitive function after ischemic stroke is unclear. We aimed to assess the association of sST2 and cognitive impairment at 3 months in acute ischemic stroke patients.
4/7/2023 1:15:00 PM +00:00
Cost-utility analysis of a consensus and evidence-based medication review to optimize and potentially reduce psychotropic drug prescription in institutionalized dementia patients
Growing evidence shows the effects of psychotropic drugs on the evolution of dementia. Until now, only a few studies have evaluated the cost-effectiveness of psychotropic drugs in institutionalized dementia patients.
4/7/2023 1:14:53 PM +00:00
Functional status and its associated factors among community-dwelling older adults in rural Nepal: Findings from a cross-sectional study
The high burden of chronic conditions, coupled with various physical, mental, and psychosocial changes that accompany the phenomenon of aging, may limit the functional ability of older adults. This study aims to assess the prevalence of poor functional status and investigate factors associated with poor functional status among community-dwelling older adults in rural communities of eastern Nepal.
4/7/2023 1:14:42 PM +00:00
Association between anemia, physical performance and cognitive function in Iranian elderly people: Evidence from Bushehr Elderly Health (BEH) program
The present study aimed to investigate the relation between anemia and hemoglobin (Hgb) concentration, physical performance, and cognitive function in a large sample of Iranian elderly population.
4/7/2023 1:14:35 PM +00:00
Neutrophil-lymphocyte ratio as a predictor of delirium in older internal medicine patients: A prospective cohort study
Delirium is a common neuropsychiatric syndrome in older hospitalized patients. Previous studies have suggested that inflammation and oxidative stress contribute to the pathophysiology of delirium. However, it remains unclear whether neutrophil-lymphocyte ratio (NLR), an indicator of systematic inflammation, is associated with delirium.
4/7/2023 1:14:29 PM +00:00
Transitions between levels of dependency among older people receiving social care – a retrospective longitudinal cohort study in a Swedish municipality
Knowledge is scarce on how needs for home help and special housing evolve among older people who begin to receive support from municipal social care. The purpose of this study was to describe baseline distributions and transitions over time between levels of dependency among older persons after being granted social care in a Swedish municipality.
4/7/2023 1:14:17 PM +00:00
Experiences of community-dwelling older people with dementia participating in a person-centred multidimensional interdisciplinary rehabilitation program
There is great need for development of feasible rehabilitation for older people with dementia. Increased understanding of this population’s experiences of rehabilitation participation is therefore important. The aim of this study was to explore the experiences of community-dwelling older people with dementia participating in a person-centred multidimensional interdisciplinary rehabilitation program.
4/7/2023 1:14:10 PM +00:00
Older people’s experiences of oral health and assisted daily oral care in short-term facilities
Older people’s oral health has improved, and many retain their natural teeth throughout their life. However, their daily oral care can be more difficult because of compromised general health and the reduced capacity for self-care that often comes with old age.
4/7/2023 1:14:04 PM +00:00
Evaluation of the Psychometric Properties of PainChek® in UK Aged Care Residents with advanced dementia
The aim of this study was to further validate PainChek®, an electronic pain assessment instrument, with a population living with dementia in a UK care home. Method: This study utilised a correlational design to evaluate the psychometric properties of PainChek® when compared to the Abbey Pain Scale (APS). Blinded paired pain assessments were completed at rest and immediately post-movement by a researcher and a nurse.
4/7/2023 1:13:56 PM +00:00
The sex difference in gait speed among older adults: How do sociodemographic, lifestyle, social and health determinants contribute?
This study explores whether a sex difference in sensitivity to (strength of the association) and/or in exposure to (prevalence) determinants of gait speed contributes to the observed lower gait speed among older women compared to men.
4/7/2023 1:13:49 PM +00:00
Sleep duration, vegetable consumption and all-cause mortality among older adults in China: A 6-year prospective study
Sleep duration and vegetable consumption are associated with mortality at old age (termed as sleepmortality linkage and vegetable-mortality linkage, respectively). Yet, little is known about the interplay of sleep duration and vegetable consumption on mortality.
4/7/2023 1:13:43 PM +00:00
Barriers and facilitators to the implementation of social robots for older adults and people with dementia: A scoping review
Psychosocial issues, such as social isolation and loneliness among older adults and people with dementia, continue to pose challenges with a rapidly aging population worldwide. Social robots are a rapidly emerging field of technology, developed to help address the psychosocial needs of this population.
4/7/2023 1:13:36 PM +00:00
Validation of perceived physical fatigability using the simplified-Chinese version of the Pittsburgh Fatigability Scale
The Pittsburgh Fatigability Scale (PFS) was developed to capture fatigue and demand in a single tool, filling a gap that no validated questionnaire existed to measure perceived fatigability. Since fatigability is a more sensitive measure of a person’s susceptibility to fatigue, we validated the simplified-Chinese version of the PFS among Chinese community-dwelling older adults.
4/7/2023 1:13:29 PM +00:00