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THE MECHANISMS OF DNA REPLICATION
Edited by David Stuart
The Mechanisms of DNA Replication http://dx.doi.org/10.5772/3433 Edited by David Stuart
Contributors
Andrey Aleksandrovich Grach, Lynne Cox, Penelope Mason, Christophe Thiriet, Angélique Galvani, Agustino Martinez-Antonio, Laura Espindola-Serna, César Quiñones-Valles, Susan Forsburg, Sarah Sabatinos, Radmila Capkova Frydrychova, James Mason, Naoki Sato, Takashi Moriyama, Apolonija Bedina Zavec, Amine Aloui, Herve Seligmann, Yoshizumi Ishino, Takeo Kubota, Maria Vittoria Di Tomaso, Alba Guarne, Lindsay Matthews, David Stuart, Douglas Maya, Mari Cruz Muñoz-Centeno, Macarena Morillo-Huesca, Sebastian Chavez, Lidia Delgado Ramos, Dianne C. Daniel, Edward Johnson, Ayuna Dagdanova, Thomas Melendy
Published by InTech
Janeza Trdine 9, 51000 Rijeka, Croatia
Copyright © 2013 InTech
All chapters are Open Access distributed under the Creative Commons Attribution 3.0 license, which allows users to download, copy and build upon published articles even for commercial purposes, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech, authors have the right to republish it, in whole or part, in any publication of which they are the author, and to make other personal use of the work. Any republication, referencing or personal use of the work must explicitly identify the original source.
Notice
Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials, instructions, methods or ideas contained in the book.
Publishing Process Manager Ana Pantar Technical Editor InTech DTP team
Cover InTech Design team
First published March, 2013 Printed in Croatia
A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechopen.com
The Mechanisms of DNA Replication, Edited by David Stuart p. cm.
ISBN 978-953-51-0991-4
free online editions of InTech Books and Journals can be found at www.intechopen.com
Contents
Preface IX
Section 1 Machines that Drive DNA Replication 1
Chapter 1
Chapter 2
Chapter 3
Chapter 4
Chapter 5
Chapter 6
Chapter 7
Pulling the Trigger to Fire Origins of DNA Replication 3 David Stuart
Replicative Helicases as the Central Organizing Motor Proteins in the Molecular Machines of the Elongating Eukaryotic Replication Fork 29
John C. Fisk, Michaelle D. Chojnacki and Thomas Melendy
The MCM and RecQ Helicase Families: Ancient Roles in DNA Replication and Genomic Stability Lead to Distinct Roles in Human Disease 59
Dianne C. Daniel*, Ayuna V. Dagdanova and Edward M. Johnson
DNA Replication in Archaea, the Third Domain of Life 91 Yoshizumi Ishino and Sonoko Ishino
Proposal for a Minimal DNA Auto-Replicative System 127 Agustino Martinez-Antonio, Laura Espindola-Serna and Cesar Quiñones-Valles
Extending the Interaction Repertoire of FHA and BRCT Domains 145
Lindsay A. Matthews and Alba Guarné
Intrinsically Disordered Proteins in Replication Process 169 Apolonija Bedina Zavec
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