Stability of the CpG island methylator phenotype during glioma progression and identification of methylated loci in secondary glioblastomas
Stability of the CpG island methylator phenotype during glioma progression and identification of methylated loci in secondary glioblastomas
Grade IV glioblastomas exist in two forms, primary (de novo) glioblastomas (pGBM) that arise without precursor lesions, and the less common secondary glioblastomas (sGBM) which develop from earlier lower grade lesions.