Pediatric biopharmaceutical classification system: Using age-appropriate initial gastric volume
Pediatric biopharmaceutical classification system: Using age-appropriate initial gastric volume
Development of optimized pediatric formulations for oral administration can be challenging, time consuming, and financially intensive process. Since its inception, the biopharmaceutical classification system (BCS) has facilitated the development of oral drug formulations destined for adults. At least theoretically, the BCS principles are applied also to pediatrics. A comprehensive age-appropriate BCS has not been fully developed. The objective of this work was to provisionally classify oral drug