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9/10/2012
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Chapter 25
Neurology
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Lesson 25.1
Anatomy, Physiology Pathophysiology, and Assessment
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Copyright © 2013 by Jones & Bartlett Learning, LLC, an Ascend Learning Company 1
9/10/2012
Learning Objectives
• Describe anatomy and physiology of nervous system.
• Outline pathophysiological changes in nervous system that may alter the cerebral perfusion pressure.
• Describe assessment of patient with nervous system disorder.
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Nervous System Anatomy and Physiology
• Divided into two parts
– Central nervous system (CNS)
– Peripheral nervous system (PNS)
• Ability of human body to maintain state of balance (homeostasis) is chiefly result of nervous system’s ability to coordinate and regulate body’s activities
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Copyright © 2013 by Jones & Bartlett Learning, LLC, an Ascend Learning Company 2
9/10/2012
Nervous System Anatomy and Physiology
• CNS consists of brain and spinal cord
– Both are encased in and protected by bone
– Total of 43 pairs of nerves originate from CNS to form PNS
– 12 pairs of cranial nerves originate from brain
– 31 pairs of spinal nerves originate from spinal cord
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Nervous System Cells
• Cells of nervous system – Neurons
• Basic units of nervous system • Connective tissue cells
– Neuroglia
• Specialized cells that protect and hold functioning neurons together
– Each neuron has three main parts
• Cell body, which has a single, relatively large nucleus with prominent nucleolus
• One or more branching projections, called dendrites • Single, elongated projection, known as axon
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Copyright © 2013 by Jones & Bartlett Learning, LLC, an Ascend Learning Company 3
9/10/2012
Nervous System Cells
• Dendrites transmit impulses to cell bodies • Axons
– Transmit impulses away from cell bodies
– Surrounded by supportive and protective sheaths formed by cytoplasmic extensions of neuroglial cells in CNS (unmyelinated axons)
– Surrounded by Schwann cells in PNS (myelinated axons)
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Nervous System Cells
• White matter
– Bundles of parallel axons with their associated sheaths are white
• Action potential
– Initiated in neuron body
– Propagated through axons via conduction pathways or nerve tracts from one area of CNS to another
• In PNS, bundles of axons and their sheaths are called nerves
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Nervous System Cells
• Gray matter
– Collections of nerve cells – Grayer in color
– Site of integration in nervous system
– Outer surface of cerebrum and cerebellum consists of gray matter
• Forms cerebral cortex and cerebellar cortex
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Copyright © 2013 by Jones & Bartlett Learning, LLC, an Ascend Learning Company 4
9/10/2012
Neuron Types
• Neurons are classified as – Sensory neurons
– Motor neurons – Interneurons
• Based on direction in which they transmit impulses
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Neuron Types
• Sensory neurons
– Transmit impulses to spinal cord and brain from all parts of body
– Also called afferent neurons • Motor neurons
– Transmit impulses in opposite direction, away from brain and spinal cord
– Transmit impulses only to muscle and glandular epithelial tissue
– Also called efferent neurons
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Neuron Types
• Interneurons
– Conduct impulses from sensory neurons to motor neurons
– Also called central or connecting neurons
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Copyright © 2013 by Jones & Bartlett Learning, LLC, an Ascend Learning Company 5
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