A cross-sectional study of global DNA methylation and risk of colorectal adenoma
A cross-sectional study of global DNA methylation and risk of colorectal adenoma
The methylation of DNA is recognized as a key epigenetic mechanism and evidence for its role in the development of several malignancies is accumulating. We evaluated the relationship between global methylation in DNA derived from normal appearing colon mucosal tissue and blood leukocytes, and colorectal adenoma risk.